Compound 401

• CAS Number :

  168425-64-7

• SKU :

  C11956-5mg

• Target :

  DNA-PK

• Applications :

  PI3K/Akt/mTOR

• Smiles :

  C1COCCN1C2=CC (=O) N3C=CC4=CC=CC=C4C3=N2

• Molecular Formula :

  C16H15N3O2

• Additionnal Information :

  Compound 401 is a synthetic inhibitor of DNA-PK (IC50=0.28 μM) and mTOR (IC50=5.3 μM) . It has no inhibition on p110α/p85α PI3K (>100 μM) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.

• Storage Conditions :

  3 years -20°C powder