Tacrolimus monohydrate

• CAS Number :

  109581-93-3

• Synonyms :

  Tacrolimus, FK506

• SKU :

  C11351-5mg

• Target :

  Phosphatase

• Applications :

  Metabolism

• Molecular Formula :

  C44H69NO12.H2O

• Additionnal Information :

  Tacrolimus monohydrate (Tacrolimus, FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP) . This inhibition blocks calcium-dependent processes, including interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis, and also has immunosuppressive, neuroregenerative and neuroprotective properties.