Rolapitant

CAT: 1568-C11058-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C11058-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
552292-08-7
Synonyms
SCH-619734
SKU
C11058-5mg
Target
Neurokinin Receptor
Applications
Neuronal Signaling
Smiles
CC (C1=CC (=CC (=C1) C (F) (F) F) C (F) (F) F) OCC2 (CCC3 (CCC (=O) N3) CN2) C4=CC=CC=C4
Molecular Formula
C25H26F6N2O2
Additionnal Information
Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.
Storage Conditions
3 years -20°C powder

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