Dehydrocostus Lactone

CAT: 1568-C09458Size: 25 mgDry Ice: YesHazardous: No
CAT#:1568-C09458Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
477-43-0
SKU
C09458-25mg
Target
IκB/IKK
Applications
NF-κB
Smiles
C=C1CCC2C (C3C1CCC3=C) OC (=O) C2=C
Molecular Formula
C15H18O2
Additionnal Information
Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
Storage Conditions
2 years -80 in solvent

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