Dehydrocostus Lactone

• CAS Number :

  477-43-0

• SKU :

  C09458-25mg

• Target :

  IκB/IKK

• Applications :

  NF-κB

• Smiles :

  C=C1CCC2C (C3C1CCC3=C) OC (=O) C2=C

• Molecular Formula :

  C15H18O2

• Additionnal Information :

  Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

• Storage Conditions :

  2 years -80 in solvent