UCB-9260

• CAS Number :

  1515888-53-5

• SKU :

  C09225-5mg

• Target :

  TNF-alpha

• Applications :

  Apoptosis

• Smiles :

  C[N]1C=C (C=N1) C2=CC3=C (C=C2) N=C (C (O) C4=CC=NC=C4) [N]3CC5=C (C) C=CC (=C5) C

• Molecular Formula :

  C26H25N5O

• Additionnal Information :

  UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.

• Storage Conditions :

  3 years -20°C powder