TAK-285

• CAS Number :

  871026-44-7

• SKU :

  C08856-5mg

• Target :

  EGFR

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC (C) (CC (=O) NCCN1C=CC2=C1C (=NC=N2) NC3=CC (=C (C=C3) OC4=CC=CC (=C4) C (F) (F) F) Cl) O

• Molecular Formula :

  C26H25ClF3N5O3

• Additionnal Information :

  TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.

• Storage Conditions :

  2 years -80 in solvent