Itraconazole

• CAS Number :

  84625-61-6

• Synonyms :

  R 51211

• SKU :

  C08596-1g

• Target :

  Hedgehog/Smoothened

• Applications :

  Stem Cells & Wnt

• Smiles :

  CCC (C) N1C (=O) N (C=N1) C2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) OCC5COC (O5) (CN6C=NC=N6) C7=C (C=C (C=C7) Cl) Cl

• Molecular Formula :

  C35H38Cl2N8O4

• Additionnal Information :

  Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.

• Storage Conditions :

  2 years -80 in solvent