Raltegravir

• CAS Number :

  518048-05-0

• Synonyms :

  MK-0518

• SKU :

  C08199-5mg

• Target :

  Integrase

• Applications :

  Microbiology

• Smiles :

  CC1=NN=C (O1) C (=O) NC (C) (C) C2=NC (=C (C (=O) N2C) O) C (=O) NCC3=CC=C (C=C3) F

• Molecular Formula :

  C20H21FN6O5

• Additionnal Information :

  Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.

• Storage Conditions :

  2 years -80 in solvent