WZ3146

• CAS Number :

  1214265-56-1

• SKU :

  C07580-5mg

• Target :

  EGFR

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC=C (C (=N3) OC4=CC=CC (=C4) NC (=O) C=C) Cl

• Molecular Formula :

  C24H25ClN6O2

• Additionnal Information :

  WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .

• Storage Conditions :

  2 years -80 in solvent