BI 2536

• CAS Number :

  755038-02-9

• SKU :

  C07526-1g

• Target :

  PLK

• Applications :

  Cell Cycle

• Smiles :

  CCC1C (=O) N (C2=CN=C (N=C2N1C3CCCC3) NC4=C (C=C (C=C4) C (=O) NC5CCN (CC5) C) OC) C

• Molecular Formula :

  C28H39N7O3

• Additionnal Information :

  BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.

• Storage Conditions :

  2 years -80 in solvent