Nutlin-3

• CAS Number :

  890090-75-2

• SKU :

  C07482-5mg

• Target :

  E3 Ligase

• Applications :

  Ubiquitin

• Smiles :

  CC (C) OC1=C (C=CC (=C1) OC) C2=NC (C (N2C (=O) N3CCNC (=O) C3) C4=CC=C (C=C4) Cl) C5=CC=C (C=C5) Cl

• Molecular Formula :

  C30H30Cl2N4O4

• Additionnal Information :

  Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.

• Storage Conditions :

  2 years -80 in solvent