Tat-nr2b9c

CAT: 1568-C06920Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C06920Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
500992-11-0
SKU
C06920-5mg
Target
Others
Applications
Others
Smiles
CCC (C) C (NC (=O) C (CO) NC (=O) C (CO) NC (=O) C (CC (C) C) NC (=O) C (CCCCN) NC (=O) C (CCCNC (N) =N) NC (=O) C (CCCNC (N) =N) NC (=O) C (CCCNC (N) =N) NC (=O) C (CCC (N) =O) NC (=O) C (CCCNC (N) =N) NC (=O) C (CCCNC (N) =N) NC (=O) C (CCCCN) NC (=O) C (CCCCN) NC (=O) C (CCCNC (N) =N) NC (=O) CNC (=O) C (N) CC1=CC=C (O) C=C1) C (=O) NC (CCC (O) =O) C (=O) NC (CO) C (=O) NC (CC (O) =O) C (=O) NC (C (C) C) C (O) =O
Molecular Formula
C105H188N42O30
Additionnal Information
Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively, and disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively, also inhibits neuronal nitric oxide synthase (nNOS) /PSD-95 interaction, and possesses neuroprotective efficacy.
Storage Conditions
3 years-20°C powder

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