2'-C-Methyladenosine

CAT: 1568-C04638Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C04638Size:5 mg
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CAS Number
15397-12-3
SKU
C04638-5mg
Target
HCV Protease
Applications
Proteases
Additionnal Information
2’-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication, with an IC50 of 0.3 μM in Huh-7 cells. It is converted intracellularly to its triphosphate form (2’-C-methyladenosine triphosphate), which acts as a chain terminator and directly inhibits the HCV RNA-dependent RNA polymerase (NS5B) with an IC50 of 1.9 μM in enzymatic assays.

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