ACY-957

• CAS Number :

  1609389-52-7

• SKU :

  C04618-1mg

• Target :

  HDAC

• Applications :

  DNA Damage/DNA Repair

• Additionnal Information :

  ACY-957 is a selective chemical inhibitor of HDAC1 and HDAC2 with an IC50 values of 7 nM, 18 nM against HDAC1/2 respectively. It induces hemoglobin protein (HbF) in primary erythroid progenitor cells, including those from sickle cell patients, offering a promising approach for treating sickle cell disease (SCD) and β-thalassemia.