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Dehydroaripiprazole

CAT: 1568-C04127Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C04127Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
129722-25-4
Synonyms
OPC-14857, DM-14857
SKU
C04127-5mg
Target
Dopamine Receptor
Applications
Neuronal Signaling
Additionnal Information
Dehydroaripiprazole (OPC-14857, DM-14857) is the active metabolite of aripiprazole, primarily metabolized by CYP3A4 and CYP2D6. It inhibits glutamate release from rat prefrontocortical nerve terminals by activating dopamine D2 and 5-HT1A receptors, reducing nerve terminal excitability and VDCC activation through a PKA-mediated signaling cascade, potentially contributing to its neuroprotective effects in excitotoxic injury.

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