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A-674563

CAT: 1568-C04071Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C04071Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
552325-73-2
SKU
C04071-5mg
Target
Akt
Applications
PI3K/Akt/mTOR
Additionnal Information
A-674563 is a selective, orally active inhibitor of Akt1 with a Ki of 11 nM. It also inhibits PKA with Ki of 16 nM and CDK2 with Ki of 46 nM. A-674563 reduces Akt downstream target phosphorylation and inhibits tumor cell proliferation in vitro with an EC50 of 0.4 μM.

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