Products for Research Use Only
RegisterLogin

Cyclosporin H

CAT: 1568-C03921Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C03921Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
83602-39-5
SKU
C03921-1mg
Additionnal Information
Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1) . Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs) . Cyclosporin H displays an additive effect when combined with Rapamycin or Prostaglandin E2. Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.

Chemical Information

Cyclosporin H

cyclosporin h has been reported in Trichoderma polysporum and Tolypocladium inflatum with data available.

CAS Number83602-39-5
PubChem CID6476564
IUPAC Name(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular FormulaC62H111N11O12
Molecular Weight1202.6
XLogP7.5
Topological Polar Surface Area279
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count12
Rotatable Bond Count15
Heavy Atom Count85
Formal Charge0
Complexity2330
SMILES
CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
InChI
InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50-,51+,52-/m1/s1
InChIKey
PMATZTZNYRCHOR-JLPRAAIDSA-N
Chemical Structure
2D Structure
2D structure of Cyclosporin H
CAS: 83602-39-5
CID: 6476564
Formula: C62H111N11O12
MW: 1202.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1202.6
XLogP37.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count12
Rotatable Bond Count15
Exact Mass1201.84136802
Monoisotopic Mass1201.84136802
Topological Polar Surface Area279 Ų
Heavy Atom Count85
Formal Charge0
Complexity2330
Isotope Atom Count0
Defined Atom Stereocenter Count12
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
C08422-50mgCyclosporin A
C08422-10mM/1mLCyclosporin A
C08422-01Cyclosporin A
C08422-1gCyclosporin A
C08422-200mgCyclosporin A
C04906-1mgCyclosporin A-d4
C04906Cyclosporin A-d4
C18300NIM811 ((Melle-4) cyclosporin)
C18300-1mgNIM811 ((Melle-4) cyclosporin)
C13887-1mgTenacissoside H

Alternative Products

CatalogName
PT_40345-01Cyclosporin-A (Cyclosporin A)
OPPA01320-1GCyclosporin A - Cyclosporin-A Protein
B1922-SCyclosporin A
7-04922Cyclosporin-A

Popular Products