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(R) -Propranolol hydrochloride

CAT: 1568-C03684-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:1568-C03684-01Size:50 mg
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CAS Number
13071-11-9
Synonyms
Dexpropranolol hydrochloride
SKU
C03684-50mg
Target
Adrenergic Receptor
Applications
Neuronal Signaling
Additionnal Information
(R) -Propranolol (hydrochloride) (Dexpropranolol hydrochloride) is a nonselective antagonist of beta-adrenergic receptor (β-adrenergic receptor (βAR) ) that competitively blocks the action of epinephrine (EPI) and norepinephrine (NE) on β1- and β2-adrenoreceptors (AR) . It exhibits anti-neuroblastoma activity and is effective in combination therapies for relapsed and refractory neuroblastoma patients.

Chemical Information

Dexpropranolol Hydrochloride

See also: Dexpropranolol (has active moiety).

CAS Number13071-11-9
PubChem CID66366
IUPAC Name(2R)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride
Molecular FormulaC16H22ClNO2
Molecular Weight295.80
Topological Polar Surface Area41.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Heavy Atom Count20
Formal Charge0
Complexity257
SMILES
CC(C)NC[C@H](COC1=CC=CC2=CC=CC=C21)O.Cl
InChI
InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1
InChIKey
ZMRUPTIKESYGQW-PFEQFJNWSA-N
Chemical Structure
2D Structure
2D structure of Dexpropranolol Hydrochloride
CAS: 13071-11-9
CID: 66366
Formula: C16H22ClNO2
MW: 295.80
Interactive 3D Structure
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Computed Properties
PropertyValue
Molecular Weight295.80
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass295.1339066
Monoisotopic Mass295.1339066
Topological Polar Surface Area41.5 Ų
Heavy Atom Count20
Formal Charge0
Complexity257
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes