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PK 11195

CAT: 1568-C03247-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C03247-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
85532-75-8
Synonyms
RP 52028
SKU
C03247-5mg
Target
Others
Applications
Others
Additionnal Information
PK 11195 (RP 52028) is a translocator protein (TSPO) ligand, a potent and selective antagonist of peripheral benzodiazepine receptorwith high affinity Ki of 3.1 nM in cerebellum and 4.1 nM in spinal cord. It is also an antagonist of human constitutive androstane receptor (hCAR), and human pregnane X receptor (PXR) . It displaces [3H] RO5-4864 from its binding sites across organs and also targets Leishmania in chemotherapy.

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