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APX2009

CAT: 1568-C02001-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:1568-C02001-03Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415030-15-7
SKU
C02001-5mg
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Additionnal Information
APX2009 is a second-generation redox-specific inhibitor of APE1/Ref-1, an essential enzyme in the base excision repair (BER) pathway. APX2009 effectively reduces breast cancer cell proliferation and colony formation.

Chemical Information

CID 71618575
CAS Number1415030-15-7
PubChem CID71618575
IUPAC Name(2E)-N,N-diethyl-2-[(3-methoxy-1,4-dioxonaphthalen-2-yl)methylidene]pentanamide
Molecular FormulaC21H25NO4
Molecular Weight355.4
XLogP3.6
Topological Polar Surface Area63.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Heavy Atom Count26
Formal Charge0
Complexity628
SMILES
CCC/C(=C\C1=C(C(=O)C2=CC=CC=C2C1=O)OC)/C(=O)N(CC)CC
InChI
InChI=1S/C21H25NO4/c1-5-10-14(21(25)22(6-2)7-3)13-17-18(23)15-11-8-9-12-16(15)19(24)20(17)26-4/h8-9,11-13H,5-7,10H2,1-4H3/b14-13+
InChIKey
WEMXCNYTFZUFSB-BUHFOSPRSA-N
Chemical Structure
2D Structure
2D structure of CID 71618575
CAS: 1415030-15-7
CID: 71618575
Formula: C21H25NO4
MW: 355.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.4
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass355.17835828
Monoisotopic Mass355.17835828
Topological Polar Surface Area63.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity628
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
E1987-01APX2009
A24286-10APX2009 10mg
A24286-50APX2009 50mg
A24286-5APX2009 5mg
A24286-1APX2009 1mg

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