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R16

CAT: 1568-C01990-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C01990-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
6325-13-9
Synonyms
NSC29869, Nrf2-IN-3
SKU
C01990-5mg
Target
Nrf2
Applications
NF-κB
Additionnal Information
R16 (NSC29869, Nrf2-IN-3) is an inhibitor of NRF2 (nuclear factor erythroid 2-related factor 2) that selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions. It significantly enhances the sensitivity of KEAP1-mutated tumor cells to cisplatin and gefitinib.

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