Products for Research Use Only
RegisterLogin

Vazegepant hydrochloride

CAT: 1568-C01892-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C01892-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1414976-20-7
Synonyms
Zavegepant, BHV-3500
SKU
C01892-5mg
Target
CGRP Receptor
Applications
Neuronal Signaling
Additionnal Information
Vazegepant hydrochloride (BHV-3500, Zavegepant), is a highly potent, selective, and structurally unique small molecule antagonist of CGRP receptor. It can also be used for the acute treatment of migraine.

Chemical Information

Zavegepant hydrochloride

Zavegepant hydrochloride is the hydrochloride salt of zavegepant. It is a calcitonin gene-related peptide receptor antagonist administered as a nasal spray for the acute treatment of migraine with or without aura in adults. It has a role as a calcitonin gene-related peptide receptor antagonist. It contains a zavegepant(1+).

CAS Number1414976-20-7
PubChem CID134819878
IUPAC NameN-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide;hydrochloride
Molecular FormulaC36H47ClN8O3
Molecular Weight675.3
Topological Polar Surface Area117
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count48
Formal Charge0
Complexity1160
SMILES
CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O.Cl
InChI
InChI=1S/C36H46N8O3.ClH/c1-24-19-25(20-28-23-37-40-33(24)28)21-32(35(46)43-17-15-42(16-18-43)29-9-11-41(2)12-10-29)39-36(47)44-13-7-26(8-14-44)30-22-27-5-3-4-6-31(27)38-34(30)45;/h3-6,19-20,22-23,26,29,32H,7-18,21H2,1-2H3,(H,37,40)(H,38,45)(H,39,47);1H/t32-;/m1./s1
InChIKey
VQDUWCSSPSOSNA-RYWNGCACSA-N
Chemical Structure
2D Structure
2D structure of Zavegepant hydrochloride
CAS: 1414976-20-7
CID: 134819878
Formula: C36H47ClN8O3
MW: 675.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight675.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass674.3459651
Monoisotopic Mass674.3459651
Topological Polar Surface Area117 Ų
Heavy Atom Count48
Formal Charge0
Complexity1160
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
C01305Arecaidine hydrochloride
C01593ACHP Hydrochloride
C01737Atrasentan hydrochloride
C01838-01Mepazine hydrochloride
C01844-01Protokylol hydrochloride
C01950-01SLF1081851 hydrochloride
C02240-01MS023 hydrochloride
C02251-01(-) -Isoproterenol hydrochloride
C02286-01Norepinephrine hydrochloride
C02036Guvacine hydrochloride

Alternative Products

CatalogName
BUP02968-01Vazegepant hydrochloride
T38734-01Vazegepant
JH918843Vazegepant HCl
HY-134992S(Rac) -Vazegepant-13C, d3
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
OR1043462-01Hydrochloride
MBS6103001-01O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (Cyclopropylmethoxyamine, Hydrochloride, Cyclopropylmethoxylamine, Hydrochloride)
C7050-01Cysteamine hydrochloride; 2-AminoeThanethiol Hydrochloride; 2-Aminoethane-1-Thiol Hydrochloride; Mercaptamine Hydrochloride

Popular Products