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TC-E5002 (KDM2/7-IN-1)

CAT: 1568-C01877-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C01877-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1453071-47-0
Synonyms
KDM2/7-IN-1
SKU
C01877-5mg
Target
Histone Demethylase
Applications
Epigenetics
Additionnal Information
TC-E5002 (KDM2/7-IN-1) is a selective inhibitor of histone demethylase KDM2/7 subfamily with IC50s of 6.8, 0.2, and 1.2 μM for KDM2A, KDM7A, and KDM7B, respectively. It is selective for the KDM2/7 subfamily over KDM4A, KDM4C, KDM5A, and KDM6A/UTX with IC50s of >120, 83, 55, and 100 μM, respectively. It exhibits antiproliferative activity, indicating its potential as an anticancer agent.

Chemical Information

N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-beta-alanine
CAS Number1453071-47-0
PubChem CID71735843
IUPAC Name3-[9-cyclopropylnonanoyl(hydroxy)amino]propanoic acid
Molecular FormulaC15H27NO4
Molecular Weight285.38
XLogP3.4
Topological Polar Surface Area77.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count12
Heavy Atom Count20
Formal Charge0
Complexity302
SMILES
C1CC1CCCCCCCCC(=O)N(CCC(=O)O)O
InChI
InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
InChIKey
NEHSERYKENINRH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-beta-alanine
CAS: 1453071-47-0
CID: 71735843
Formula: C15H27NO4
MW: 285.38
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight285.38
XLogP33.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count12
Exact Mass285.19400834
Monoisotopic Mass285.19400834
Topological Polar Surface Area77.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity302
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
E1793-1gTC-E5002 (KDM2/7-IN-1)
A16373-25KDM2/7-IN-1 (TC-E 5002) 25mg
A16373-10KDM2/7-IN-1 (TC-E 5002) 10mg
A16373-50KDM2/7-IN-1 (TC-E 5002) 50mg
A16373-5KDM2/7-IN-1 (TC-E 5002) 5mg
A16373-1KDM2/7-IN-1 (TC-E 5002) 1mg
B7148-10TC 1
ARI0110TC-1
T212177-01TC-PTP-IN-1
256822-01TC AQP1 1

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