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Paxilline

CAT: 1568-C01608-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:1568-C01608-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
57186-25-1
SKU
C01608-1mg
Target
ATPase
Applications
Transmembrane Transporters
Additionnal Information
Paxilline, an indole alkaloid mycotoxin derived from Penicillium paxilli, potently inhibits the BK channel by exerting its effects through direct channel inhibition. Additionally, Paxilline also functions as an inhibitor of sarco/endoplasmic reticulum Ca2+-stimulated ATPase (SERCA), with IC50 values ranging from 5 μM-50 μM, depending on the SERCA isoform. Paxilline also possesses significant anticonvulsant and neuroprotective effects.

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