GS-621763

• CAS Number :

  2647442-13-3

• SKU :

  C01480-5mg

• Target :

  SARS-CoV

• Applications :

  Microbiology

• Smiles :

  CC (C) C (=O) OCC1OC (C#N) (C (OC (=O) C (C) C) C1OC (=O) C (C) C) C2=CC=C3[N]2N=CN=C3N

• Additionnal Information :

  GS-621763, an orally bioavailable prodrug of GS-441524, shows a dose-dependent antiviral effect on SARS-CoV-2 reporter virus expressing nanoluciferase (SARS-CoV-2 nLUC) replication with an EC50 of 2.8 μM, also inhibits reporter SARS-CoV-2 expressing firefly luciferase (SARS-CoV-2 Fluc) replication with EC50 of 0.125 μM.

• Storage Conditions :

  3 years -20°C powder