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MK-8722

CAT: 1568-C01438-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:1568-C01438-03Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1394371-71-1
SKU
C01438-5mg
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
OC1COC2C (COC12) OC3=NC4=NC (=C (Cl) C=C4[NH]3) C5=CC=C (C=C5) C6=CC=CC=C6
Additionnal Information
MK-8722 is a potent, direct, allosteric activator of all 12 mammalian pan-AMPK complexes.
Storage Conditions
3 years -20°C powder

Chemical Information

MK-8722

an AMP-activated protein kinase activator

CAS Number1394371-71-1
PubChem CID89558344
IUPAC Name(3R,3aR,6R,6aR)-6-[[6-chloro-5-(4-phenylphenyl)-1H-imidazo[4,5-b]pyridin-2-yl]oxy]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol
Molecular FormulaC24H20ClN3O4
Molecular Weight449.9
XLogP3.8
Topological Polar Surface Area89.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity645
SMILES
C1[C@H]([C@@H]2[C@H](O1)[C@@H](CO2)OC3=NC4=NC(=C(C=C4N3)Cl)C5=CC=C(C=C5)C6=CC=CC=C6)O
InChI
InChI=1S/C24H20ClN3O4/c25-16-10-17-23(28-24(26-17)32-19-12-31-21-18(29)11-30-22(19)21)27-20(16)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-10,18-19,21-22,29H,11-12H2,(H,26,27,28)/t18-,19-,21-,22-/m1/s1
InChIKey
XQMNBTZLYOOAGA-UGESXGAOSA-N
Chemical Structure
2D Structure
2D structure of MK-8722
CAS: 1394371-71-1
CID: 89558344
Formula: C24H20ClN3O4
MW: 449.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight449.9
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass449.1142338
Monoisotopic Mass449.1142338
Topological Polar Surface Area89.5 Ų
Heavy Atom Count32
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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