I-191

• CAS Number :

  1690172-25-8

• SKU :

  C01067-5mg

• Target :

  PAR

• Applications :

  GPCR & G Protein

• Smiles :

  CC (C) (C) C1=CC (=N[N]2C=C (N=C12) C (=O) N3CCNC (=O) C3 (C) C) C4=CC=C (F) C=C4

• Additionnal Information :

  I-191 is a potent PAR2 antagonist that inhibits multiple PAR2-induced signaling pathways and functional responses. I-191 also inhibits ERK1/2 phosphorylation, RhoA activation, and inhibition of forskolin-stimulated cAMP accumulation induced by micromolar concentrations of biased ligand GB88.

• Storage Conditions :

  3 years -20°C powder