Products for Research Use Only
RegisterLogin

Dorzagliatin 25mg

CAT: 0628-A22297-25Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0628-A22297-25Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1191995-00-2

Chemical Information

Dorzagliatin

Dorzagliatin is a secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methylpentanoic acid with the amino group of (2R)-3-(3-amino-1H-pyrrol-1-yl)propane-1,2-diol. It is an allosteric glucokinase activator developed by Hua Medicine for the treatment of type 1 and 2 diabetes mellitus , and diabetic kidney disease. It has a role as an enzyme activator and a hypoglycemic agent. It is a secondary carboxamide, a primary alcohol, a pyrroline, a diol, a member of pyrazoles, an aromatic ether, a secondary alcohol, a tertiary amino compound, an enone and a member of monochlorobenzenes.

CAS Number1191995-00-2
PubChem CID57920094
IUPAC Name(2S)-2-[3-(2-chlorophenoxy)-5-oxo-2H-pyrrol-1-yl]-N-[1-[(2R)-2,3-dihydroxypropyl]pyrazol-3-yl]-4-methylpentanamide
Molecular FormulaC22H27ClN4O5
Molecular Weight462.9
XLogP1.6
Topological Polar Surface Area117
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Heavy Atom Count32
Formal Charge0
Complexity691
SMILES
CC(C)C[C@@H](C(=O)NC1=NN(C=C1)C[C@H](CO)O)N2CC(=CC2=O)OC3=CC=CC=C3Cl
InChI
InChI=1S/C22H27ClN4O5/c1-14(2)9-18(22(31)24-20-7-8-26(25-20)11-15(29)13-28)27-12-16(10-21(27)30)32-19-6-4-3-5-17(19)23/h3-8,10,14-15,18,28-29H,9,11-13H2,1-2H3,(H,24,25,31)/t15-,18+/m1/s1
InChIKey
HMUMWSORCUWQJO-QAPCUYQASA-N
Chemical Structure
2D Structure
2D structure of Dorzagliatin
CAS: 1191995-00-2
CID: 57920094
Formula: C22H27ClN4O5
MW: 462.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight462.9
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Exact Mass462.1669977
Monoisotopic Mass462.1669977
Topological Polar Surface Area117 Ų
Heavy Atom Count32
Formal Charge0
Complexity691
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
A22297-5Dorzagliatin 5mg
A22297-100Dorzagliatin 100mg
A22297-50Dorzagliatin 50mg
A22297-10Dorzagliatin 10mg
A22297-1Dorzagliatin 1mg
A22297-2Dorzagliatin 2mg
A22297-10mM-DDorzagliatin 10mM * 1mL in DMSO
A13047-25A-205804 25mg
A14328-25Sagopilone 25mg
A24249-25LXG6403 25mg

Alternative Products

CatalogName
B8799-5Dorzagliatin
HY-109030R-01Dorzagliatin (Standard)
1050-25mgDAPI, 25mg
1871-25mgTDM, 25mg
1920-25mgMitomycin C, 25mg
OOMC00085-25MGOOMC00085-25MG - Volasertib
OOMC00086-25MGOOMC00086-25MG - Favipiravir
OOMC00087-25MGOOMC00087-25MG - Ponatinib
OOMC00021-25MGOOMC00021-25MG - Carfilzomib

Popular Products