Products for Research Use Only
RegisterLogin

Rhosin 5mg

CAT: 0628-A21504-5Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0628-A21504-5Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1173671-63-0

Chemical Information

Rhosin

Rhosin is a D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs. It has a role as a RhoA inhibitor, a RhoC inhibitor and an antineoplastic agent. It is a hydrazone, a quinoxaline derivative and a D-tryptophan derivative.

CAS Number1173671-63-0
PubChem CID9552914
IUPAC Name(2R)-2-amino-3-(1H-indol-3-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamide
Molecular FormulaC20H18N6O
Molecular Weight358.4
XLogP1.7
Topological Polar Surface Area109
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity541
SMILES
C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)N/N=C/C3=CC4=NC=CN=C4C=C3)N
InChI
InChI=1S/C20H18N6O/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18/h1-9,11-12,16,24H,10,21H2,(H,26,27)/b25-11+/t16-/m1/s1
InChIKey
FGYHLIHEFHCMPP-FVWOBLMASA-N
Chemical Structure
2D Structure
2D structure of Rhosin
CAS: 1173671-63-0
CID: 9552914
Formula: C20H18N6O
MW: 358.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight358.4
XLogP31.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass358.15420922
Monoisotopic Mass358.15420922
Topological Polar Surface Area109 Ų
Heavy Atom Count27
Formal Charge0
Complexity541
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
A21648-5Rhosin hydrochloride 5mg
A21504-50Rhosin 50mg
A21504-10Rhosin 10mg
A21504-25Rhosin 25mg
A21504-100Rhosin 100mg
A21648-10Rhosin hydrochloride 10mg
A21648-25Rhosin hydrochloride 25mg
A21648-2Rhosin hydrochloride 2mg
A21648-100Rhosin hydrochloride 100mg
A21648-50Rhosin hydrochloride 50mg

Alternative Products

CatalogName
MBS5769925Rhosin
HY-12646-01Rhosin (hydrochloride)
MBS3846075-01Rhosin hydrochloride

Popular Products