PF-06840003 10mg
Chemical Information
Pf-06840003 is iDO1 Inhibitor PF-06840003 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities. Upon administration, IDO1 inhibitor PF-06840003 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine.
| CAS Number | 198474-05-4 |
| PubChem CID | 23063810 |
| IUPAC Name | 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione |
| Molecular Formula | C12H9FN2O2 |
| Molecular Weight | 232.21 |
| XLogP | 0.9 |
| Topological Polar Surface Area | 62 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 360 |
| Property | Value |
|---|---|
| Molecular Weight | 232.21 |
| XLogP3 | 0.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 232.06480570 |
| Monoisotopic Mass | 232.06480570 |
| Topological Polar Surface Area | 62 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 360 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
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