BOS-172722 10mg

Chemical Information
BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.
| CAS Number | 1578245-44-9 |
| PubChem CID | 73386890 |
| IUPAC Name | 8-N-(2,2-dimethylpropyl)-2-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine |
| Molecular Formula | C24H30N8O |
| Molecular Weight | 446.5 |
| XLogP | 4.3 |
| Topological Polar Surface Area | 103 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 8 |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 616 |
| Property | Value |
|---|---|
| Molecular Weight | 446.5 |
| XLogP3 | 4.3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 8 |
| Exact Mass | 446.25425761 |
| Monoisotopic Mass | 446.25425761 |
| Topological Polar Surface Area | 103 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 616 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Related Products
Alternative Products
Popular Products

Eukaryotic Prion Protein (PRNP)
SKU: TRV-037236-01|Size: 10 µg

The Creatinine Companion (Creatinine Assay)
SKU: 1012|Size: 1 Kit

Albuwell M (Mouse Albumin ELISA)
SKU: 1011|Size: 1 Each

Albuwell M (Mouse Albumin ELISA)
SKU: 1011|Size: 1 Kit

ARHGEF39
SKU: 555463-01|Size: 50 µg

Hexarelin
SKU: MBS826675-01|Size: 1 mg

Recombinant Saccharophagus degradans Probable inorganic polyphosphate/ATP-NAD kinase (ppnK)
SKU: MBS1426819-01|Size: 0.02 mg (E-Coli)

Human placenta protein14 (PP14) ELISA Kit
SKU: QY-E01330|Size: 96 Tests

Recombinant Human Alkaline Phosphatase/ALPI Protein (His Tag)
SKU: PKSH030690|Size: 50 µg

Human Canine alpha 1-Microglobulin ELISA Kit (Colorimetric)
SKU: NBP2-60496|Size: 1 Kit

Staphylococcus aureus antibody
SKU: 10-S30A|Size: 500 ug

Staphylococcus aureus antibody
SKU: 10-S30C|Size: 500 ug

Staphylococcus aureus antibody
SKU: 20C-CR1274RP|Size: 1 ml

Staphylococcus Aureus, Antibody
SKU: GWB-20A150|Size: 1 mg

Staphylococcus aureus Antibody
SKU: GWB-17415A|Size: 0.2 mg

Staphylococcus aureus Antibody
SKU: GWB-10480A|Size: 0.2 mg

Staphylococcus Aureus, Antibody
SKU: GWB-3C8362|Size: 1 mg

Staphylococcus aureus Antibody
SKU: GWB-A22B32|Size: 0.2 mg

Staphylococcus aureus Antibody
SKU: GWB-13BBD1|Size: 1 mg

Staphylococcus aureus antibody
SKU: 10-S30C|Size: 0.5 mg
