Nitroflurbiprofen

• Description :

  Nitroflurbiprofen is a cyclooxygenase (COX) inhibitor with nitric oxide (NO) -donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.

• Product Name Alternative :

  HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen

• UNSPSC :

  12352005

• Target :

  COX

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/Nitroflurbiprofen.html

• Purity :

  99.64

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  O=C(OCCCCO[N+]([O-])=O)C(C)C1=CC=C(C2=CC=CC=C2)C(F)=C1

• Molecular Formula :

  C19H20FNO5

• Molecular Weight :

  361.36

• References & Citations :

  [1]Laleman W, et al. Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portalhypertension in rats. Gastroenterology. 2007 Feb;132 (2) :709-19.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  COX

• CAS Number :

  [158836-71-6]