SY-1365 50mg

CAT: 0628-A18482-50Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0628-A18482-50Size:50 mg

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CAS Number

1816989-16-8

Chemical Information

Mevociclib

Mevociclib (SY-1365) is a selective CDK7 inhibitor. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors.

CAS Number	1816989-16-8
PubChem CID	118426108
IUPAC Name	N-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-methylcyclohexyl]-5-[[(E)-4-(dimethylamino)but-2-enoyl]amino]pyridine-2-carboxamide
Molecular Formula	C31H35ClN8O2
Molecular Weight	587.1
XLogP	4.2
Topological Polar Surface Area	128
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Heavy Atom Count	42
Formal Charge	0
Complexity	952

SMILES

C[C@@]1(CCC[C@H](C1)NC2=NC=C(C(=N2)C3=CNC4=CC=CC=C43)Cl)NC(=O)C5=NC=C(C=C5)NC(=O)/C=C/CN(C)C

InChI

InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1

InChIKey

SCJNYBYSTCRPAO-LXBQGUBHSA-N

Chemical Structure

2D Structure

CAS: 1816989-16-8

CID: 118426108

Formula: C31H35ClN8O2

MW: 587.1

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	587.1
XLogP3	4.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	586.2571501
Monoisotopic Mass	586.2571501
Topological Polar Surface Area	128 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	952
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
A18482-100	SY-1365 100mg
A18482-10	SY-1365 10mg
A18482-5	SY-1365 5mg
A18482-1	SY-1365 1mg
A24106-50	SY-LB-35 50mg
A24279-50	SY-5609 (CDK7-IN-3) 50mg
A24106-10	SY-LB-35 10mg
A24106-100	SY-LB-35 100mg
A24106-5	SY-LB-35 5mg
A18678-50	BKI-1369 50mg

Alternative Products

Catalog	Name
MBS133151	SY-1365
HY-180355	SY-5102
E1041-25mg	SY-5609
T37859-01	SY-640
MBS8535091-01	Phospho-Met (Tyr 1365)

SY-1365 50mg

Chemical Information

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