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AAI101 2mg

CAT: 0628-A18341-2Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0628-A18341-2Size:2 mg
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CAS Number
1001404-83-6

1001404-83-6

PubChem
cas1001404-83-6
modify2026-05-17
descriptionEnmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections. Enmetazobactam is used as cefepime-sparing therapy by preventing its breakdown by ESBL.
synonyms
Enmetazobactam1001404-83-6AAI-101OCID-509080VUN7L00C
(2S,3S,5R)-3-Methyl-3-[(3-methyltriazol-3-ium-1-yl)methyl]-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
EXBLIFEP COMPONENT ENMETAZOBACTAM
(2S,3S,5R)-3-Methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
1H-1,2,3-Triazolium, 3-(((2S,3S,5R)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-3-yl)methyl)-1-methyl-, inner salt
(2S,3S,5R)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4lambda6-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
+ 15 more
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