Picumeterol

• UNSPSC Description:

  Picumeterol (GR114297A) is a potent and selective β2-adrenoceptor agonist with bronchodilator and anti-bronchoconstrictor effects. Picumeterol produces long-lasting relaxation of airways smooth muscle both in vitro and in vivo. Picumeterol is cleared from plasma through a rapid and extensive hepatic metabolism. Picumeterol is proming for rasearch of asthma and related diseases[1][2].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/picumeterol.html

• Smiles:

  O[C@H](C1=CC(Cl)=C(C(Cl)=C1)N)CNCCCCCCOCCC2=CC=CC=N2

• Molecular Weight:

  426.38

• References & Citations:

  [1]Weersink EJ, et al. Picumeterol: dissociation of improvement in lung function and reduction of airways hyperresponsiveness in asthmatics. Br J Clin Pharmacol. 1997 Feb;43(2):169-76.|[2]Barrow A, et al. Kinetics and disposition of picumeterol in animals. Xenobiotica. 1995 Sep;25(9):993-1007.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  130641-36-0