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Picumeterol

CAT: 0804-HY-124950Size: 1 EachDry Ice: NoHazardous: No
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Description
Picumeterol (GR114297A) is a potent and selective β2-adrenoceptor agonist with bronchodilator and anti-bronchoconstrictor effects. Picumeterol produces long-lasting relaxation of airways smooth muscle both in vitro and in vivo. Picumeterol is cleared from plasma through a rapid and extensive hepatic metabolism. Picumeterol is proming for rasearch of asthma and related diseases[1][2].
CAS Number
130641-36-0
Product Name Alternative
GR114297A
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/picumeterol.html
Smiles
O[C@H](C1=CC(Cl)=C(C(Cl)=C1)N)CNCCCCCCOCCC2=CC=CC=N2
Molecular Formula
C21H29Cl2N3O2
Molecular Weight
426.38
References & Citations
[1]Weersink EJ, et al. Picumeterol: dissociation of improvement in lung function and reduction of airways hyperresponsiveness in asthmatics. Br J Clin Pharmacol. 1997 Feb;43 (2) :169-76.|[2]Barrow A, et al. Kinetics and disposition of picumeterol in animals. Xenobiotica. 1995 Sep;25 (9) :993-1007.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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