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Recombinant Human Progesterone receptor (PGR), partial

CAT: 0399-CSB-EP017875HU3-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-EP017875HU3-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Nuclear receptor subfamily 3 group C member 3; PR
Abbreviation
Recombinant Human PGR protein, partial
Gene Name
PGR
UniProt
P06401
Expression Region
323-419aa
Organism
Homo sapiens (Human)
Target Sequence
LLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPL
Tag
N-terminal 6xHis-ABP-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Others
Relevance
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor
Endotoxin
Not test
Purity
Greater than 95% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
16.9 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

UniProtKB · P06401

Progesterone receptor

PRGR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06401
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PGR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PR
EC number
—
Processing
—
Secondary accessions
A7LQ08, A7X8B0, B4E3T0, Q8TDS3, Q9UPF7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Cellular component

CytoplasmMembraneMitochondrionMitochondrion outer membraneNucleus

Molecular function

DNA-bindingReceptor

PTM

Isopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Ligand

Lipid-bindingMetal-bindingSteroid-bindingZinc

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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