Pulegone (Standard)

• UNSPSC Description:

  Pulegone (Standard) is the analytical standard of Pulegone. This product is intended for research and analytical applications. Pulegone, the major chemical constituent of Nepeta catariaessential oil which is an aromatic herb, is one of avian repellents[1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations[2].

• Target Antigen:

  Endogenous Metabolite; TRP Channel

• Type:

  Reference Standards

• Related Pathways:

  Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pulegone-standard.html

• Smiles:

  O=C1/C(CC[C@@H](C)C1)=C(C)/C

• Molecular Weight:

  152.23

• References & Citations:

  [1]Božović M, et al. Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry. Molecules. 2017 Feb 14;22(2).|[2]Majikina A, et al. Involvement of nociceptive transient receptor potential channels in repellent action of pulegone. Biochem Pharmacol. 2018 May;151:89-95.

• Shipping Conditions:

  Room temperature

• CAS Number:

  89-82-7