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CD63 Rabbit mAb IHC Kit

CAT: 0808-KM3738-01Size: 3 mLDry Ice: NoHazardous: No
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CAT#:0808-KM3738-01Size:3 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD63 is a lysosomal membrane glycoprotein, which is widely expressed in hematopoietic and non-hematopoietic cells, such as sweat glands, Langerhan islands, pituitary, pancreas, peribronchial glands and prostate cells. CD63, as a tumor suppressor gene, is expressed in malignant melanoma and inhibits its proliferation and metastasis. The expression of CD63 is negatively correlated with invasion and metastasis of malignant melanoma. It is strongly expressed in early stage of melanoma and can be used in the study of melanoma.
Synonyms
CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; Lysosome integral membrane protein 1; Melanoma-associated antigen ME491; CD63
Gene Name
CD63
Gene ID
967
Swiss Prot
P08962
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 200 of the human CD63 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can recognize human CD63 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
CD63