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Osteocalcin (AB2210) Rabbit mAb

CAT: 0808-M3548-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0808-M3548-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Synonyms
Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
Gene Name
BGLAP
Gene ID
632
Swiss Prot
P02818
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB; IHC; IF; IP; ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:100-1:500 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein) protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)