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MiTF (AB1692) Rabbit mAb

CAT: 0808-M3057-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0808-M3057-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
MITF, BHLHE32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32
Gene Name
MITF
Gene ID
4286
Swiss Prot
O75030
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IHC, 1:200-1:500 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of MiTF protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
MiTF

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