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MTCO2 (AB1663) Rabbit mAb

CAT: 0808-M3032-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0808-M3032-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cofactor:Copper A. , disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110], also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood. , disease:Defects in MT-CO2 are associated with tumor formation. , function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. , similarity:Belongs to the cytochrome c oxidase subunit 2 family.
Synonyms
Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)
Gene Name
MT-CO2 COII COXII MTCO2
Gene ID
4513
Swiss Prot
P00403
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein (or fragment) . This information is considered to be commercially sensitive.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
WB, IHC, IF, IP, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of MTCO2 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
MTCO2

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