DB818 (dihydrochloride)
CAT:
804-HY-122623A-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DB818 (dihydrochloride)
- UNSPSC Description: DB818 dihydrochloride is the dihydrochloride salt form of DB818 (HY-122623). DB818 dihydrochloride is an inhibitor for Homeobox A9 (HOXA9). DB818 dihydrochloride reduces the formation of HOXA9-DNA complexes, inhibits the growth and induces apoptosis in AML cell lines OCI/AML3, MV4-11, and THP-1[1].
- Target Antigen: Apoptosis
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/db818-dihydrochloride.html
- Purity: 99.43
- Solubility: H2O : 5 mg/mL (ultrasonic;warming)
- Smiles: N=C(C1=CC=C(C2=CC=C(C3=NC4=CC=C(C(N)=N)C=C4N3)S2)C=C1)N.Cl.Cl
- Molecular Weight: 433.36
- References & Citations: [1]Sonoda Y, et al. Effects of HOXA9 Inhibitor DB818 on the Growth of Acute Myeloid Leukaemia Cells. Anticancer Res. 2021 Apr;41(4):1841-1847.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported