Cyclohexanecarboxylic acid

• Description:

  Cyclohexanecarboxylic acid is a Valproate structural analogue. Cyclohexanecarboxylic acid is an essential intermediate for the aromatization of Shikimic acid (HY-N0130) by mammals. Cyclohexanecarboxylic acid has anticonvulsant action[1][2][3].

• Product Name Alternative:

  Hexahydrobenzoic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H319

• Target:

  Drug Intermediate; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cyclohexanecarboxylic-acid.html

• Purity:

  99.85

• Solubility:

  DMSO : 50 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C (C1CCCCC1) O

• Molecular Formula:

  C7H12O2

• Molecular Weight:

  128.17

• Precautions:

  H302, H319

• References & Citations:

  [1]Liu MJ, et al. Pharmacokinetics and pharmacodynamics of valproate analogues in rats. IV. Anticonvulsant action and neurotoxicity of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid. Epilepsia. 1994 Jan-Feb;35 (1) :234-43.|[2]Rho EM, et al. The aerobic metabolism of cyclohexanecarboxylic acid by Acinetobacter anitratum. Biochem J. 1975 Apr;148 (1) :11-5. |[3]Brewster D, et al. The metabolism of cyclohexanecarboxylic acid in the isolated perfused rat liver. Xenobiotica. 1977 Oct;7 (10) :601-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  98-89-5