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Ruboxyl

CAT: 0804-HY-119261Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119261Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ruboxyl is an anthracycline antibiotic with antitumor activity. Ruboxyl inhibits colorectal cancer (CRC) liver metastasis in mice by 84%, suppresses B16 melanoma growth, and increases the survival rate of mice with L1210 or L5178Y leukemia[1][2].
CAS Number
80214-88-6
UNSPSC
12352005
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ruboxyl.html
Smiles
O=C1C2=C(C3=C(C(O)=C2C(C4=C1C=CC=C4OC)=O)[C@@H](O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C[C@@](/C(C)=N\N=C6CC(C)(N(C(C)(C/6)C)O)C)(O)C3)O.Cl
Molecular Formula
C36H47ClN4O10
Molecular Weight
731.23
References & Citations
[1]Leonetti C, et al. Ruboxyl, a new nitroxyl derivative of daunorubicin - acute toxicity and antitumor effect in animals. Int J Oncol. 1993 Oct;3 (4) :615-8.|[2]Sirovich I, et al. Activity of ruboxyl, a nitroxyl derivative of daunorubicin, on experimental models of colorectal cancer metastases. Tumour Biol. 1999 Sep-Oct;20 (5) :270-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5775891Ruboxyl

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