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Macelignan

CAT: 0804-HY-N0064-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0064-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macelignan ((+) -Anwulignan; Anwuligan) is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities[1][2][3].
CAS Number
107534-93-0
Product Name Alternative
(+) -Anwulignan; Anwuligan
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Macelignan.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@H](C)[C@H](C)CC2=CC=C(OCO3)C3=C2)C=C1OC
Molecular Formula
C20H24O4
Molecular Weight
328.40
Precautions
H302, H315, H319
References & Citations
[1]Anggakusuma, et al. Effects of macelignan isolated from Myristica fragrans Houtt. on UVB-induced matrix metalloproteinase-9 and cyclooxygenase-2 in HaCaT cells. J Dermatol Sci|[2]Jiyoung Yeo, et al. Effects of a multi-herbal extract on type 2 diabetes. Chin Med. 2011 Mar 4;6:10.|[3]Chun-Ai Cui, et al. Macelignan attenuates LPS-induced inflammation and reduces LPS-induced spatial learning impairments in rats. Neurosci Lett. 2008 Dec 19;448 (1) :110-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2

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