Angiotensin I/II (1-5) (TFA)

Angiotensin I/II (1-5) (TFA)

• UNSPSC Description: Angiotensin I/II 1-5 TFA is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin I/II 1-5 TFA is an active mediator of renin-angiotensin system to stimulate atrial natriuretic peptide (ANP) secretion via Mas R and PI3K-Akt-NOS pathway.[1][2].
• Target Antigen: Angiotensin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/angiotensin-i-ii-1-5-tfa.html
• Purity: 99.78
• Solubility: DMSO : 20 mg/mL (ultrasonic)
• Smiles: CC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC1=CC=C(C=C1)O)=O)C(O)=O)C.OC(C(F)(F)F)=O
• Molecular Weight: 778.77
• References & Citations: [1]Erdös EG, et al. Conversion of angiotensin I to angiotensin II. Am J Med. 1976 May 31;60(6):749-59.|[2]Yu L, et al. Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor. Peptides. 2016 Dec;86:33-41.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported