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AYK004

CAT: 0804-HY-159916Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159916Size:1 Each
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Description
AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity [1].
CAS Number
3031612-90-2
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ayk004.html
Smiles
O=C1NC2=C(N1CCCCCN3CCNCC3)N=C(OC(C(F)(F)F)C)N=C2N
Molecular Formula
C17H26F3N7O2
Molecular Weight
417.43
References & Citations
[1]Zhou et al, Adenine derivative, preparation method and application thereof, and immune adjuvant system, China, CN117263939, 2023-12-22
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7; TLR8

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