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A-78773

CAT: 0804-HY-120606Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120606Size:1 Each
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Description
A-78773 is a 5-lipoxygenase inhibitor. A-78773 can inhibit the formation of LTB4 in human whole blood and human neutrophils, with IC50 values of 85 nM and 20 nM, respectively. A-78773 can be used in the study of inflammation-related diseases[1].
CAS Number
141579-67-1
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a-78773.html
Smiles
O=C(N(O)C(C#CC1=CC=C(O1)OC2=CC=C(C=C2)F)C)N
Molecular Formula
C15H13FN2O4
Molecular Weight
304.27
References & Citations
[1]Basha A, et al. Second generation leukotriene biosynthesis inhibitors[J]. Pure and applied chemistry, 1994, 66 (10-11) : 2197-2200.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5776182A 78773

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