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Atagabalin

CAT: 0804-HY-14856Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14856Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atagabalin (PD 0200390) is a selective GABA (gamma-aminobutyric acid) receptor agonist with antianxiety and sedative effects. Atagabalin enhances the activity of the GABA receptor by binding to the α2δ subunit of the GABA receptor, thereby increasing the GABA mediated inhibition. This enhancement results in reduced excitability of neurons, helping to reduce anxiety and improve sleep. Atagabalin can be used to study neuropsychiatric disorders, anxiety or sleep disorders[1].
CAS Number
223445-75-8
Product Name Alternative
PD 0200390
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atagabalin.html
Smiles
O=C(O)CC1(CN)C[C@H](C)[C@@H](C)C1
Molecular Formula
C10H19NO2
Molecular Weight
185.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Corrigan B, et al. Effect of renal impairment on the pharmacokinetics of PD 0200390, a novel ligand for the voltage‐gated calcium channel alpha‐2‐delta subunit[J]. British journal of clinical pharmacology, 2009, 68 (2) : 174-180.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

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MBS5779824Atagabalin
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A13402-50Atagabalin 50mg
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A13402-5Atagabalin 5mg
GTR19219689-01(Iso) -Atagabalin HCl
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