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Beclomethasone-d5

CAT: 0804-HY-B1540SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1540SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Beclomethasone-d5 is the deuterium labeled Beclometasone. Beclometasone (Beclomethasone) is a prototype glucocorticoid receptor agonist.
CAS Number
1263143-48-1
UNSPSC
12352211
Target
Glucocorticoid Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Endocrinology
Solubility
10 mM in DMSO
Smiles
Cl[C@@]12[C@](CC([2H])([2H])C([C@@]2(C=C3)C)=C([2H])C3=O)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](O)([C@H](C4)C)C(C([2H])([2H])O)=O)C
Molecular Formula
C22H24D5ClO5
Molecular Weight
413.95
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]He S, et al. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227 (4) :431-45.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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