Beclomethasone-d5

Beclomethasone-d5

• CAS Number: 1263143-48-1
• UNSPSC Description: Beclomethasone-d5 is the deuterium labeled Beclometasone. Beclometasone (Beclomethasone) is a prototype glucocorticoid receptor agonist.
• Target Antigen: Glucocorticoid Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Immunology/Inflammation;Others;Vitamin D Related/Nuclear Receptor
• Field of Research: Inflammation/Immunology; Endocrinology
• Solubility: 10 mM in DMSO
• Smiles: Cl[C@@]12[C@](CC([2H])([2H])C([C@@]2(C=C3)C)=C([2H])C3=O)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](O)([C@H](C4)C)C(C([2H])([2H])O)=O)C
• Molecular Weight: 413.95
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]He S, et al. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported